Ketamine, which was once known only as a party drug, can be used recreationally or as a treatment for depression and other mental health issues under doctor supervision.

氯胺酮曾经只是一种派对药物，现在可以在医生指导下用于娱乐或治疗抑郁症和其他精神健康问题。

According to the full autopsy report obtained by Business Insider, Perry was using ketamine therapy but the amount found in his system — about as much as would be used in general anesthesia — could not have been from his last treatment a week and a half prior.

根据商业内幕网获得的完整尸检报告，派瑞正在使用氯胺酮治疗，但在他体内发现的氯胺酮量——大约相当于全身麻醉的用量——不可能是他一周半前最后一次治疗时使用的。

Perry's opioid replacement therapy and his previous heart condition exacerbated the effects of the ketamine before he drowned, the report found.

报告发现，派瑞在溺水前接受的阿片类药物替代疗法和他之前的心脏病加剧了氯胺酮的作用。

Perry had coronary artery disease, which is when plaque builds up on the walls of the arteries of the heart, causing them to narrow. This condition, plus the ketamine, led to "cardiovascular overstimulation," according to the report.

派瑞患有冠状动脉疾病，即斑块堆积在心脏动脉壁上，导致动脉狭窄。报告称，这种疾病加上氯胺酮导致了“心血管过度刺激”。

Perry was taking buprenorphine, a medication used to treat opioid use disorder. While buprenorphine and ketamine can be combined at low doses, high doses of both drugs can cause people to breathe too slowly and lose consciousness.

派瑞正在服用丁丙诺啡，这是一种用于治疗阿片类药物使用障碍的药物。虽然低剂量的丁丙诺啡和氯胺酮可以合用，但高剂量的这两种药物会导致患者呼吸过慢并失去知觉。

The report said that Perry "lapsed into unconsciousness" and was likely submerged in his pool.

报告称，派瑞“陷入昏迷”，很可能是溺死在浴缸中。

02 一生戒毒65次

Perry was open about his struggles with alcoholism and drug addiction.At 49, he had a near-death experience after his colon burst from opioid use.

派瑞曾公开自己与酗酒和吸毒的斗争。49岁时，他曾因服用阿片类药物导致结肠破裂而濒临死亡。

A 2022 interview with ABC News' Diane Sawyer revealed the "Friends" actor attended rehab at least 15 times, detoxed 65 times, and went to 6,000 AA meetings.

2022 年，这位《老友记》的男主角在与美国广播公司新闻频道的戴安·索耶的采访中透露，自己至少进过15次戒毒所，尝试了65次的戒毒，参加过6000次嗜酒者互诫会。

In his memoir, "Friends, Lovers and the Big Terrible Thing," Perry wrote that his addiction stemmed from a "lifetime of feeling abandoned" and a "desperate need for love."

派瑞在他的回忆录《老友、爱人和大麻烦》中写道，他的毒瘾源于“一生中被遗弃的感觉”和“对爱的迫切需求”。

Perry told People he decided to open up about his struggles in the hopes it would help others."I wanted to share when I was safe from going into the dark side of everything again," Perry said. "I had to wait until I was pretty safely sober — and away from the active disease of alcoholism and addiction — to write it all down. And the main thing was, I was pretty certain that it would help people."

派瑞告诉《人物》，他决定公开自己的挣扎，希望能帮助他人。派瑞说：“当我不再陷入黑暗的时候，我想分享一下。我必须等到自己完全清醒——远离酗酒和毒瘾这种活动性疾病——之后才能写下来。最重要的是，我非常确信这本书会对人们有所帮助。”

03 人间再无“六人行”

马修·派瑞曾在回忆录中提到《老友记》的搭档们当年对他的陪伴和照料：“就像企鹅团队一样，一只企鹅病了，其他的都会围过来、撑着它继续向前走。”

他还特别提到了“瑞秋”的饰演者詹妮弗·安妮斯顿（Jennifer Aniston）是第一个向他伸出援手的好友。

Jennifer Aniston says she was texting her "Friends" costar Matthew Perry just hours before his death, and that he seemed happy and healthy.

詹妮弗·安妮斯顿说，她在《老友记》的主演马修·派瑞去世前几个小时还在给他发短信，说他看起来很开心很健康。

Aniston told Variety in an interview published Monday: "He was happy. He was healthy. He had quit smoking. He was getting in shape. He was happy — that's all I know."

在周一发表的一篇采访中，安妮斯顿告诉《综艺》杂志：“他很开心。他很健康。他已经戒烟了。他的身材正在好转。他很开心——我只知道这些。”

"I want people to know he was really healthy, and getting healthy," said Aniston. "He was on a pursuit. He worked so hard. He really was dealt a tough one."

安妮斯顿说：“我想让大家知道，他真的很健康，而且正在变得越来越健康。”“他正在追求自己想要的生活。他付出了巨大的努力。他真的遭遇了很大的不幸。”

"I miss him dearly. We all do. Boy, he made us laugh really hard," she continued.

“我非常想念他。我们都是这样。那个男孩，他总让我们开怀大笑，”她继续说道。

马修去世两天后，《老友记》五位主演詹妮弗·安妮斯顿、马特·勒布朗、大卫·休默、柯特妮·考克斯和丽莎·库卓发表了一份联合声明：

"We are all so utterly devastated by the loss of Matthew. We were more than just cast mates. We are a family," the statement read.

声明中提到：“我们都为失去马修而伤心欲绝。我们不仅仅是搭档。我们是一家人。”

They added: "There is so much to say, but right now we're going to take a moment to grieve and process this unfathomable loss. In time we will say more, as and when we are able."

他们补充说：“有很多话要说，但现在我们需要一些时间哀悼和处理这一难以接受的事实。也许一段时间后，我们会再说些什么。”

如今再看六人的合照，

我们的心情再也回不到从前。

愿天堂没有痛苦！

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